Monoclonal Antibodies - HDAC8 Mouse Monoclonal antibody

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HDAC8 Mouse Monoclonal antibody

Catalog #：EAB22575

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22575-100UL	In Stock	100ul	€258.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	42
Conjugate	Unconjugate
Specificity	HDAC8 Mouse Monoclonal antibody detects endogenous levels of HDAC8 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Histone deacetylase 8; HD8; WTS; RPD3; CDA07; CDLS5; KDAC8; MRXS6; HDACL1; HDAC8
Gene Aliases	HDAC8
UniProt ID	Q9BY41
Entrez Gene ID	55869

Product Description

HDAC8(Histone deacetylase 8) is a member of the histone deacetylase family. HDAC8 is primarily located in the nucleus and plays a crucial role in the regulation of gene expression through the modification of chromatin structure. By removing acetyl groups from lysine residues on histones, HDAC8 contributes to the condensation of chromatin, leading to transcriptional repression. This process is vital for maintaining cellular homeostasis and regulating developmental processes, as aberrant HDAC activity has been implicated in various cancers and other diseases. HDAC8 interacts with several other proteins, including transcription factors and co-repressors, which further modulates gene regulation.

Product Image Gallery
Western blot analysis of extracts on Hela, MCF7, HepG2 cells, using HHDAC8 Mouse Monoclonal antibody (EAB22575) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol