SKU-Pack Size | Availability | Size | Price | |
EAB14748-30UL | In Stock | 30ul | €115.70 | |
EAB14748-100UL | In Stock | 100ul | €258.70 | |
EAB14748-200UL | In Stock | 200ul | €440.70 |
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SBT BioChem Srl | Phone£º+39 05 7156 8147 |
Via Ponte di Bagnolo, 811 Bologna, | E-mail£ºinfo@sbtbiochem.it | |
Italy | Italy | Web£ºwww.sbtbiochem.it |
Product Information | |
Applications | WB, IHC-P, IF, ELISA |
Species Reactivity | Human, Mouse |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:50-300¡¡ IF=1:50-300 |
MW (kDa) | 168 |
Conjugate | Unconjugate |
Specificity | TRAP220/MED1 Rabbit Polyclonal Antibody detects endogenous levels of TRAP220/MED1 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | Mediator complex subunit 1; PBP; CRSP1; RB18A; TRIP2; PPARBP; CRSP200; DRIP205; DRIP230; PPARGBP; TRAP220; MED1 |
Gene Aliases | MED1 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
TRAP220 also known as MED1 is integral to forming functional transcriptional machinery. TRAP220 is primarily located in the nucleus, where TRAP220 facilitates hormone-induced transcriptional activation by binding to nuclear receptors, including thyroid hormone receptors and vitamin D receptors. Nuclear localization of TRAP220 allows precise regulation of gene expression in response to hormonal signals, impacting various physiological processes such as metabolism, development, and cellular differentiation. TRAP220 is widely expressed in tissues such as skeletal muscle, heart, and placenta, highlighting TRAP220′s importance in both developmental and metabolic pathways. Through interactions with other components of the TRAP complex, making TRAP220 a significant target for studies related to gene regulation and endocrine signaling. |
Product Image Gallery | |
![]() Western blot analysis of extracts on HuvEc, Jurkat cells, using TRAP220/MED1 Rabbit Polyclonal Antibody (EAB14748) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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Specific Protocols | |