Polyclonal Antibodies - Phospho-TRAP220/MED1 (Thr1457) Rabbit Polyclonal Antibody

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Phospho-TRAP220/MED1 (Thr1457) Rabbit Polyclonal Antibody

Catalog #：EAB14749

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14749-30UL	In Stock	30ul	€141.70
EAB14749-100UL	In Stock	100ul	€297.70
EAB14749-200UL	In Stock	200ul	€479.70

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email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Monkey
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	168
Conjugate	Unconjugate
Specificity	Phospho-TRAP220/MED1 (Thr1457) Rabbit Polyclonal Antibody detects endogenous levels of TRAP220/MED1 only when phosphorylated at Thr1457.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	MED1; ARC205; CRSP1; CRSP200; DRIP205; DRIP230; PBP; PPARBP; PPARGBP; RB18A; TRAP220; TRIP2
Gene Aliases	MED1
UniProt ID	Q15648
Entrez Gene ID	5469

Product Description

TRAP220 also known as MED1 is integral to forming functional transcriptional machinery. TRAP220 is primarily located in the nucleus, where TRAP220 facilitates hormone-induced transcriptional activation by binding to nuclear receptors, including thyroid hormone receptors and vitamin D receptors. Nuclear localization of TRAP220 allows precise regulation of gene expression in response to hormonal signals, impacting various physiological processes such as metabolism, development, and cellular differentiation. TRAP220 is widely expressed in tissues such as skeletal muscle, heart, and placenta, highlighting TRAP220′s importance in both developmental and metabolic pathways. Through interactions with other components of the TRAP complex, making TRAP220 a significant target for studies related to gene regulation and endocrine signaling.

Product Image Gallery
Western blot analysis of extracts on HuvEc cells treated with Serum, using Phospho-TRAP220/MED1 (Thr1457) Rabbit Polyclonal Antibody (EAB14749) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol