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p47phox Rabbit Polyclonal Antibody
Catalog #£ºEAB13494
  SKU-Pack Size Availability Size Price
EAB13494-30UL In Stock 30ul €115.70
EAB13494-100UL In Stock 100ul €258.70
EAB13494-200UL In Stock 200ul €440.70
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Product Information
Applications WB, IHC-P, IF, ELISA
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000¡¡
IHC-P=1:50-300¡¡
IF=1:50-300
MW (kDa) 45
Conjugate Unconjugate
Specificity p47phox Rabbit Polyclonal Antibody detects endogenous levels of p47phox protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Neutrophil cytosol factor 1; CGD1; NCF-1; NCF1A; NOXO2; NCF-47K; p47phox; SH3PXD1A; p47-phox; NCF1
Gene Aliases NCF1
UniProt ID

P14598

Entrez Gene ID

653361

Product Description

p47phox also known as NOXO2, SH3PXD1A, NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. p47phox plays a crucial role in the immune response by participating in the activation of the NADPH oxidase complex, which is essential for the production of reactive oxygen species in neutrophils and other phagocytic cells. This process is vital for the destruction of pathogens, and mutations in p47phox have been linked to chronic granulomatous disease, a hereditary condition that impairs the immune system′s ability to fight infections. p47phox structure includes two Src homology 3 (SH3) domains, which are important for interaction with p67-phox, another key component of the NADPH oxidase complex.

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Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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