Recombinant Antibodies - COL17A1 Rabbit Monoclonal Antibody

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COL17A1 Rabbit Monoclonal Antibody

Catalog #：EAB21338

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21338-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IP=1:10-100　 IHC-P=1:50-200　 IF/ICC=1:50-200
MW (kDa)	150
Conjugate	Unconjugate
Specificity	COL17A1 Rabbit Monoclonal Antibody detects endogenous levels of COL17A1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Collagen type XVII alpha 1; Collagen XVII; ERED; JEB4; BP180; BPA-2; BPAG2; LAD-1; BA16H23.2; COL17A1
Gene Aliases	COL17A1
UniProt ID	Q9UMD9
Entrez Gene ID	1308

Product Description

COL17A1 also known as Collagen type XVII alpha, BP180 is a collagen family hemidesmosome anchorage molecule of basal keratinocytes that promotes stable epidermal-dermal adhesion and wound healing. COL17A1 is critical for maintaining keratocyte and hair follicle stem cells, promoting cell motility and increased self-renewing capability. The protein functions by organizing actin and keratin filament networks via its interaction with intracellular scaffold protein plectin (PLEC) and integrin β4 in the hemidesmosomes. High expression of COL17A1 is associated with cervical, colorectal, pancreatic, and lung cancers. It induces a tumor-favorable microenvironment and promotes invasion and metastasis.

Product Image Gallery
Western blot analysis of extracts on A431, HT29 cells, using COL17A1 Rabbit Monoclonal Antibody (EAB21338) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Mouse skin tissue, using COL17A1 Rabbit Monoclonal Antibody (EAB21338) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol