Recombinant Antibodies - Phospho-p95/NBS1 (Ser343) Rabbit Monoclonal Antibody

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Phospho-p95/NBS1 (Ser343) Rabbit Monoclonal Antibody

Catalog #：EAB22821

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22821-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC
Species Reactivity	Human
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IP=1:10-100　 IHC-P=1:50-200　 IF/ICC=1:50-200
MW (kDa)	85
Conjugate	Unconjugate
Specificity	Phospho-p95/NBS1 (Ser343) Rabbit Monoclonal Antibody detects endogenous levels of p95/NBS1 only when phosphorylated at Ser343.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Nijmegen breakage syndrome 1; Nibrin; ATV; NBS; P95; NBS1; AT-V1; AT-V2; hNbs1; NBN
Gene Aliases	NBN
UniProt ID	O60934
Entrez Gene ID	4683

Product Description

p95/NBS1 also known as NBS, NBS1, P95, NBN, Nibrin is a component of the MRE11/RAD50/NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity, particularly in repairing double-strand breaks, which are among the most lethal forms of DNA damage. p95/NBS1 functions as part of a complex with Mre11 and Rad50, forming the MRE11/RAD50/NBS1 (MRN) complex that is essential for recognizing and processing DNA breaks. p95/NBS1′s importance is underscored by its absence in Nijmegen breakage syndrome (NBS) patients, who exhibit increased sensitivity to ionizing radiation and predisposition to cancer due to defective DNA repair mechanisms.

Product Image Gallery
Western blot analysis of extracts on Jurkat cells treated with Etopside, using using Phospho-p95/NBS1 (Ser343) Rabbit Monoclonal Antibody (EAB22821) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide. Predicted band size: 85 kDa; Observed band size: 95 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol