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Stat6 Rabbit Monoclonal Antibody
Catalog #£ºEAB21472
  SKU-Pack Size Availability Size Price
EAB21472-100UL In Stock 100ul €297.70
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Product Information
Applications WB, IP, IHC-P, IF/ICC
Species Reactivity Human, Mouse
Host / Isotype Rabbit IgG
Clonality Monoclonal
Applications Dilutions WB=1:500-2000¡¡
IP=1:10-100¡¡
IHC-P=1:50-200¡¡
IF/ICC=1:50-200¡¡
MW (kDa) 94
Conjugate Unconjugate
Specificity STAT6 Rabbit Monoclonal Antibody detects endogenous levels of STAT6 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Signal transducer and activator of transcription 6; HIES6; STAT6B; STAT6C; D12S1644; IL-4-STAT; STAT6
Gene Aliases STAT6
UniProt ID

P42226

Entrez Gene ID

6778

Product Description

Stat6 is a member of the STAT family of transcription factors. Stat6 plays a crucial role in mediating interleukin-4 (IL-4) signaling effects, which are essential for T helper cell differentiation and immune response regulation. Upon IL-4 binding to its receptor, Stat6 undergoes phosphorylation, leading to dimerization and nuclear translocation, where Stat6 activates transcription of genes involved in immune regulation and inflammation. This process is vital for Th2 cell development, which helps combat extracellular pathogens and contributes to allergic responses. Stat6′s ability to modulate gene expression in response to cytokine signaling highlights its importance in both normal immune function and pathological conditions, such as asthma and other allergic diseases.

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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