Monoclonal Antibodies - Btk Mouse Monoclonal Antibody

Location：Home > Antibodies > Primary Antibodies > Monoclonal Antibodies

Btk Mouse Monoclonal Antibody

Catalog #：EAB21559

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21559-100UL	In Stock	100ul	$298.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Monkey
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:100-500　 IF/ICC=1:100-500
MW (kDa)	76
Conjugate	Unconjugate
Specificity	Btk Mouse Monoclonal Antibody detects endogenous levels of Btk protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	AGMX1; AI528679; AT; ATK; BPK; BTK; IMD1; PSCTK1; xid; XLA; Emb
Gene Aliases	BTK
UniProt ID	Q06187
Entrez Gene ID	695

Product Description

Btk also known as Bruton tyrosine kinase, BTK plays a crucial role in B cell development and signaling, making Btk essential for the immune response. Mutations in Btk can lead to X-linked agammaglobulinemia, a condition characterized by a significant reduction in antibody production and increased susceptibility to infections, highlighting Btk′s importance in maintaining immune system integrity. Btk is primarily localized in the cytoplasm and is recruited to the plasma membrane upon B cell receptor activation, where Btk participates in downstream signaling pathways that promote B cell maturation and proliferation.

Product Image Gallery
Western blot analysis of extracts on HEK293, K562, Jurkat cells, using Btk Mouse Monoclonal Antibody (EAB21559) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol