Recombinant Antibodies - αE-Catenin Rabbit Monoclonal Antibody

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αE-Catenin Rabbit Monoclonal Antibody

Catalog #：EAB21621

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21621-100UL	In Stock	100ul	￡251.90

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IP, IHC-P, IF/ICC, FC
Species Reactivity	Human, Mouse ,Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IP=1:10-100　 IHC-P=1:50-200　 IF/ICC=1:50-200　 FC=1:10-100
MW (kDa)	100
Conjugate	Unconjugate
Specificity	αE-Catenin Rabbit Monoclonal Antibody detects endogenous levels of αE-Catenin protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Catenin alpha 1; MDBS2; MDPT2; CAP102; CTNNA1
Gene Aliases	CTNNA1
UniProt ID	P35221
Entrez Gene ID	1495

Product Description

αE-catenin also known as catenin alpha 1, CTAAN1 is a member of the catenin family of proteins. αE-catenin plays a crucial role in E-cadherin-mediated cell-cell adhesion by linking E-cadherin to the cytoskeleton via interactions with β- or γ-catenin and actin filaments. αE-catenin is essential for maintaining the integrity of adherens junctions, which are vital for tissue architecture and cellular communication. αE-catenin is predominantly located in the neuroepithelial precursor cells of the developing cortical ventricular zone in the brain, where αE-catenin is involved in regulating cell density and the developmental hedgehog signaling pathway. The interactions between αE-catenin and vinculin are particularly important for the assembly of the apical junction complex in epithelial tissues, highlighting αE-catenin′s role in maintaining cellular structure and function.

Product Image Gallery
Western blot analysis of extracts on Hela, A431, HepG2 cells, using αE-Catenin Rabbit Monoclonal Antibody (EAB21621) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol