Recombinant Antibodies - Rad18 Rabbit Monoclonal Antibody

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Rad18 Rabbit Monoclonal Antibody

Catalog #：EAB21702

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21702-100UL	In Stock	100ul	$343.50

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF/ICC, FC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-200　 IF/ICC=1:50-200　 FC=1:10-100
MW (kDa)	56
Conjugate	Unconjugate
Specificity	Rad18 Rabbit Monoclonal Antibody detects endogenous levels of Rad18 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	RAD18 E3 ubiquitin protein ligase; RNF73; RAD18
Gene Aliases	RAD18
UniProt ID	Q9NS91
Entrez Gene ID	56852

Product Description

Rad18 plays a crucial role in post-replication repair of damaged DNA, which is vital for maintaining genomic stability and preventing mutations that could lead to cancer. Specifically, Rad18 is involved in recruiting ubiquitin-conjugating enzymes within the Rad6 pathway, facilitating modification of proteins essential for DNA repair processes. Rad18 interacts with other key proteins, such as Rad54, to ensure effective repair of chromosomal DNA. This interaction helps fill gaps in daughter strands during replication of damaged DNA, thereby preserving genetic material integrity. Rad18 is predominantly localized in the nucleus, where DNA damage response functions occur.

Product Image Gallery
Western blot analysis of extracts on 293T, NIH/3T3 cells, using Rad18 Rabbit Monoclonal Antibody (EAB21702) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol