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ACE2(Angiotensin converting enzyme 2) also known as ACEH is a potent vasopressor hormone. By converting angiotensin II into angiotensin-(1-7), ACE2 helps to counteract the effects of angiotensin II, thereby promoting vasodilation and reducing blood pressure. ACE2 plays a crucial role in the renin-angiotensin system, primarily functioning as a negative regulator of angiotensin II. This balance is vital for maintaining cardiovascular health and fluid homeostasis, making ACE2 an important target for therapeutic interventions in conditions such as hypertension and heart failure. Additionally, ACE2 is expressed predominantly in cardiac, renal, and testicular tissues, which highlights its significance in organ-specific functions and its potential role in various pathophysiological conditions.