| SKU-Pack Size | Availability | Size | Price | |
| EAB21786-100UL | In Stock | 100ul | $343.50 |
| Please select the country you are in to find your local distributor. |
| EbioCell | Phone:(540) 808-3925 | |
| Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
| Canada | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
| Product Information | |
| Applications | WB, IF/ICC |
| Species Reactivity | Human |
| Host / Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:500-2000 IF/ICC=1:50-200 |
| MW (kDa) | 53 |
| Conjugate | Unconjugate |
| Specificity | IRF-6 Rabbit Monoclonal Antibody detects endogenous levels of IRF-6 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
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| Product Bioinformatics | |
| Synonym(s) | Interferon regulatory factor 6; LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1; IRF6 |
| Gene Aliases | IRF6 |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IRF-6(Interferon regulatory factor-6) is a member of the interferon regulatory transcription factor (IRF) family. IRF-6 plays a crucial role in regulating gene expression during development, particularly in epidermis formation and palate development. Proper IRF-6 function is essential for preventing congenital defects such as cleft lip and palate, highlighting IRF-6′s importance in developmental biology. Mutations in IRF-6 have been linked to these conditions, underscoring IRF-6′s significance in both normal development and disease. Additionally, IRF-6 interacts with other proteins in the interferon regulatory factor family, which collectively regulate immune responses and cellular growth, further emphasizing IRF-6′s role in maintaining cellular homeostasis and responding to environmental signals. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on HEK293 cells, using IRF-6 Rabbit Monoclonal Antibody (EAB21786) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 53 kDa; Observed band size: 70 kDa |
| Specific Protocols | |