Recombinant Antibodies - IRF-6 Rabbit Monoclonal Antibody

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IRF-6 Rabbit Monoclonal Antibody

Catalog #：EAB21786

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21786-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, IF/ICC
Species Reactivity	Human
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IF/ICC=1:50-200
MW (kDa)	53
Conjugate	Unconjugate
Specificity	IRF-6 Rabbit Monoclonal Antibody detects endogenous levels of IRF-6 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Interferon regulatory factor 6; LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1; IRF6
Gene Aliases	IRF6
UniProt ID	O14896
Entrez Gene ID	3664

Product Description

IRF-6(Interferon regulatory factor-6) is a member of the interferon regulatory transcription factor (IRF) family. IRF-6 plays a crucial role in regulating gene expression during development, particularly in epidermis formation and palate development. Proper IRF-6 function is essential for preventing congenital defects such as cleft lip and palate, highlighting IRF-6′s importance in developmental biology. Mutations in IRF-6 have been linked to these conditions, underscoring IRF-6′s significance in both normal development and disease. Additionally, IRF-6 interacts with other proteins in the interferon regulatory factor family, which collectively regulate immune responses and cellular growth, further emphasizing IRF-6′s role in maintaining cellular homeostasis and responding to environmental signals.

Product Image Gallery
Western blot analysis of extracts on HEK293 cells, using IRF-6 Rabbit Monoclonal Antibody (EAB21786) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 53 kDa; Observed band size: 70 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol