Recombinant Antibodies - RUNX2 Rabbit Monoclonal Antibody

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RUNX2 Rabbit Monoclonal Antibody

Catalog #：EAB21796

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21796-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat, Dog
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IP=1:10-100 IHC-P=1:100-500　　 IF/ICC=1:100-500
MW (kDa)	57
Conjugate	Unconjugate
Specificity	RUNX2 Rabbit Monoclonal Antibody detects endogenous levels of RUNX2 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	RUNX family transcription factor 2; CCD; AML3; CCD1; CLCD; OSF2; CBFA1; OSF-2; PEA2aA; PEBP2aA; CBF-alpha-1; RUNX2
Gene Aliases	RUNX2
UniProt ID	Q13950
Entrez Gene ID	860

Product Description

RUNX2 also known as AML-3, PEBP2αA, CBFA1, Osf2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. RUNX2 plays a critical role in skeletal development and mineralization, functioning as a transcription factor that regulates the expression of genes essential for osteoblast differentiation and bone formation. RUNX2 stimulates the differentiation of mesenchymal stem cells into osteoblasts for proper skeletal development and promotes chondrocyte hypertrophy, which is crucial for endochondral ossification. RUNX2 drives endothelial cell migration and vascular invasion during bone development, highlighting RUNX2′s importance in both skeletal and vascular systems.

Product Image Gallery
Western blot analysis of extracts on MDA-MB-231, NIH/3T3 cells, using RUNX2 Rabbit Monoclonal Antibody (EAB21796) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol