| SKU-Pack Size | Availability | Size | Price | |
| EAB21800-100UL | In Stock | 100ul | €297.70 |
| Please select the country you are in to find your local distributor. |
| Betaclonal | Phone£º+34 (0)91 471 6763 | |
| 29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
| Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
| Product Information | |
| Applications | WB, IHC-P, IF/ICC |
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:50-200 IF/ICC=1:100-500¡¡ |
| MW (kDa) | 119 |
| Conjugate | Unconjugate |
| Specificity | HDAC4 Rabbit Monoclonal Antibody detects endogenous levels of HDAC4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
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| Product Bioinformatics | |
| Synonym(s) | Histone deacetylase 4; HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A; NEDCHF; NEDCHID; HDAC4 |
| Gene Aliases | HDAC4 |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HDAC4(Histone deacetylase 4) is a member of the histone deacetylase family. HDAC4 plays a crucial role in the regulation of gene expression through function as a histone deacetylase, which removes acetyl groups from lysine residues on histones, leading to chromatin condensation and transcriptional repression. This process is vital for maintaining cellular homeostasis and regulating developmental processes, as aberrant expression or activity of HDAC4 has been implicated in various diseases, including cancer and neurodegenerative disorders. Additionally, HDAC4 interacts with several other proteins, such as transcription factor MEF2, which is involved in muscle differentiation and neuronal function, highlighting importance in cellular signaling pathways. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on Hela, NIH/3T3, HEK293 cells, using HDAC4 Rabbit Monoclonal Antibody (EAB21800) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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| Specific Protocols | |