Monoclonal Antibodies - Sox11 Mouse Monoclonal Antibody

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Sox11 Mouse Monoclonal Antibody

Catalog #：EAB22215

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22215-100UL	In Stock	100ul	€258.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, FC
Species Reactivity	Human
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:100-500　 FC=1:50-200
MW (kDa)	47
Conjugate	Unconjugate
Specificity	Sox11 Mouse Monoclonal Antibody detects endogenous levels of Sox11 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	SRY-box transcription factor 11; CSS9; MRD27; IDDMOH; SOX11
Gene Aliases	SOX11
UniProt ID	P35716
Entrez Gene ID	6664

Product Description

Sox11 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Sox11 plays a pivotal role in neural development. Sox11 contains a high mobility group (HMG) box DNA-binding domain, which is essential for function as a transcriptional regulator. Sox11 is crucial for the differentiation and maintenance of neural progenitor cells, influencing cell fate decisions during the development of the central nervous system. Proper functioning of Sox11 is vital, as dysregulation of Sox11 expression has been linked to various neurodevelopmental disorders and may contribute to the pathogenesis of certain cancers. With evolutionary conservation and significant role in developmental processes, Sox11 serves as an important marker for studying neural development and associated diseases.

Product Image Gallery

Western blot analysis of extracts on Y79 cells, using Sox11 Mouse Monoclonal Antibody (EAB22215) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Predicted band size: 47 kDa; Observed band size: 72 kDa

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue, using Sox11 Mouse Monoclonal Antibody (EAB22215) at 1:200 dilution.

Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissue, using Sox11 Mouse Monoclonal Antibody (EAB22215) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol