Recombinant Antibodies - Phospho-ATP-citrate lyase (Thr447/Ser451) Rabbit Monoclonal Antibody

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Phospho-ATP-citrate lyase (Thr447/Ser451) Rabbit Monoclonal Antibody

Catalog #：EAB21885

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21885-100UL	In Stock	100ul	$388.50

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	121
Conjugate	Unconjugate
Specificity	Phospho-ATP-citrate lyase (Thr447/Ser451) Rabbit Monoclonal Antibody detects endogenous levels of ATP-citrate lyase only when phosphorylated at Thr447/Ser451.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	ATP citrate lyase; ACL; ATPCL; CLATP; ACLY
Gene Aliases	ACLY
UniProt ID	P53396
Entrez Gene ID	47

Product Description

ATP-citrate synthase also known as ATP-citrate lyase, citrate cleavage enzyme is a cytoplasmic homotetramer that belongs to the succinate/malate CoA ligase family, with its gene located on chromosome 17q12-q21. This enzyme plays a crucial role in cellular metabolism by catalyzing the conversion of citrate and CoA into acetyl-CoA and oxaloacetate. Acetyl-CoA is a vital substrate for fatty acid and cholesterol biosynthesis, making ATP-citrate synthase essential for energy production and lipid metabolism. Additionally, ATP-citrate synthase is significant in the biosynthesis of acetylcholine in nervous tissue, highlighting its importance in neurotransmission and overall brain function.

Product Image Gallery
Western blot analysis of extracts on K562 cells, using Phospho-ATP-citrate lyase (Thr447/Ser451) Rabbit Monoclonal Antibody (EAB21885) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol