| SKU-Pack Size | Availability | Size | Price | |
| EAB21845-100UL | In Stock | 100ul | €258.70 |
| Please select the country you are in to find your local distributor. |
| OlaSciences | Phone£º+33 (0) 9 77 4001 556 | |
| 87, rue des Suisses 65000 Nanterre, | E-mail£ºola@olasciences.com | |
| France | France | Web£ºwww.olasciences.com |
| Product Information | |
| Applications | WB, FC, ELISA |
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse IgG2a |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:500-2000 FC=1:50-200 |
| MW (kDa) | 44 |
| Conjugate | Unconjugate |
| Specificity | Cdc37 Mouse Monoclonal Antibody detects endogenous levels of Cdc37 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
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| Product Bioinformatics | |
| Synonym(s) | Cell division cycle 37; P50CDC37; CDC37 |
| Gene Aliases | CDC37 |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cdc37(Cell division cycle 37) is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. Cdc37 plays a crucial role in cell cycle regulation by facilitating the formation of cyclin-dependent kinase 4 (Cdk4) and cyclin D1 complex, essential for G1 to S phase transition. Cdc37 forms a stable complex with heat shock protein 90 (Hsp90), important for stability and function of various client proteins involved in cell cycle regulation. Proper functioning of Cdc37 and associated protein interactions are critical for maintaining cellular homeostasis and preventing uncontrolled cell proliferation, which can lead to cancer. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on A431, HEK293, LNcap cells, using Cdc37 Mouse Monoclonal Antibody (EAB21845) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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| Specific Protocols | |