Monoclonal Antibodies - Cdc37 Mouse Monoclonal Antibody

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Cdc37 Mouse Monoclonal Antibody

Catalog #：EAB21845

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21845-100UL	In Stock	100ul	￡218.90

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, FC, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Mouse IgG2a
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000 FC=1:50-200
MW (kDa)	44
Conjugate	Unconjugate
Specificity	Cdc37 Mouse Monoclonal Antibody detects endogenous levels of Cdc37 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Cell division cycle 37; P50CDC37; CDC37
Gene Aliases	CDC37
UniProt ID	Q16543
Entrez Gene ID	11140

Product Description

Cdc37(Cell division cycle 37) is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. Cdc37 plays a crucial role in cell cycle regulation by facilitating the formation of cyclin-dependent kinase 4 (Cdk4) and cyclin D1 complex, essential for G1 to S phase transition. Cdc37 forms a stable complex with heat shock protein 90 (Hsp90), important for stability and function of various client proteins involved in cell cycle regulation. Proper functioning of Cdc37 and associated protein interactions are critical for maintaining cellular homeostasis and preventing uncontrolled cell proliferation, which can lead to cancer.

Product Image Gallery
Western blot analysis of extracts on A431, HEK293, LNcap cells, using Cdc37 Mouse Monoclonal Antibody (EAB21845) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol