P55317

HNF3α also known as FOXA1 is a member of the forkhead class of DNA-binding proteins. plays a crucial role in regulating gene expression in the liver and other tissues, and proves essential for proper development of the endoderm during embryogenesis. HNF3α is involved in transcriptional regulation of genes vital for liver function, including those responsible for glucose metabolism and lipid homeostasis. HNF-3α′s ability to interact with other members of the hepatocyte nuclear factor family, such as HNF1 and HNF4, underscores its importance in maintaining metabolic processes and cellular differentiation. HNF3α has been implicated in regulating genes involved in body axis formation during gastrulation, highlighting a multifaceted role in development and metabolism.