P25445

FAS also known as CD95, TNFRSF6 is a member of the TNF-receptor superfamily. FAS plays a crucial role in regulating apoptosis, which is the process of programmed cell death that is essential for maintaining cellular homeostasis and immune system function. FAS mediates apoptosis to eliminate virus-infected or transformed cells, thereby contributing to the body′s defense mechanisms against malignancies and infections. FAS is a cell surface glycoprotein that belongs to a receptor family that includes CD40 and tumor necrosis factor receptors, and is expressed on a wide range of lymphoid cell lines. FAS interaction with FAS-L is vital for triggering the apoptotic signaling cascade, highlighting the importance of this pathway in immune responses.