Monoclonal Antibodies - IRF-4 Mouse Monoclonal Antibody

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IRF-4 Mouse Monoclonal Antibody

Catalog #：EAB22007

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22007-100UL	In Stock	100ul	$298.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
Canada	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　　 IHC-P=1:100-500 IF/ICC=1:100-500
MW (kDa)	52
Conjugate	Unconjugate
Specificity	IRF-4 Mouse Monoclonal Antibody detects endogenous levels of IRF-4 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Interferon regulatory factor 4; MUM1; LSIRF; SHEP8; IMD131; NF-EM5; IRF4
Gene Aliases	IRF4
UniProt ID	Q15306
Entrez Gene ID	3662

Product Description

IRF-4 also known as MUM1 is a member of the IRF family of DNA-binding factors, which plays a crucial role in the immune system as a transcriptional activator that regulates the expression of genes involved in immune responses, particularly in lymphoid cells. IRF-4 is essential for the differentiation of T helper 2 cells and the development of plasma cells, which are vital for antibody production. IRF-4′s ability to bind to the interferon-stimulated response element (ISRE) of the major histocompatibility complex (MHC) class I promoter underscores IRF-4′s importance in modulating immune responses and maintaining immune homeostasis. Additionally, IRF-4 interacts with other proteins, such as PU.1, which further highlights IRF-4′s role in the regulation of gene expression within the immune system.

Product Image Gallery

Western blot analysis of extracts on Daudi cells, using IRF-4 Mouse Monoclonal Antibody (EAB22007) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Immunohistochemical analysis of paraffin-embedded Human colon tissue, using IRF-4 Mouse Monoclonal Antibody (EAB22007) at 1:200 dilution.

Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using IRF-4 Mouse Monoclonal Antibody (EAB22007) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol