Recombinant Antibodies - MKK3/MKK6 Rabbit Monoclonal Antibody

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MKK3/MKK6 Rabbit Monoclonal Antibody

Catalog #：EAB21130

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21130-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC, FC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IP=1:10-100　 IHC-P=1:50-200　 IF/ICC=1:50-200　 FC=1:10-100
MW (kDa)	39/37
Conjugate	Unconjugate
Specificity	MKK3/MKK6 Rabbit Monoclonal Antibody detects endogenous levels of MKK3/MKK6 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Mitogen-activated protein kinase kinase 3; Mitogen-activated protein kinase kinase 6; MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2; MEK6; MKK6; CRCMSL; MAPKK6; PRKMK6; SAPKK3; SAPKK-3; MAP2K3; MAP2K6
Gene Aliases	MAP2K3/MAP2K6
UniProt ID	P46734, P52564
Entrez Gene ID	5606, 5608

Product Description

MKK3/MKK6 is a protein that plays a crucial role in the MAPK signaling pathway, specifically in the activation of p38 MAP kinase and JNK MAP kinases, which are essential for cellular responses to stress and inflammation. MKK3/MKK6 recognizes a protein vital for regulating various physiological processes, including cell differentiation, proliferation, and apoptosis. Dysregulation of this pathway can lead to various diseases, including cancer and inflammatory disorders, making MKK3/MKK6 a significant target for therapeutic intervention. Understanding MKK3/MKK6 interactions with other proteins in the MAPK pathway can provide insights into regulatory mechanisms and potential roles in disease progression.

Product Image Gallery
Western blot analysis of extracts on Hela, MCF7 cells, using MKK3/MKK6 Rabbit Monoclonal Antibody (EAB21130) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol