Recombinant Antibodies - PLK1 Rabbit Monoclonal Antibody

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PLK1 Rabbit Monoclonal Antibody

Catalog #：EAB21898

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB21898-30UL	In Stock	30ul	€141.70
EAB21898-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500
MW (kDa)	68
Conjugate	Unconjugate
Specificity	PLK1 Rabbit Monoclonal Antibody detects endogenous levels of PLK1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Polo like kinase 1; PLK; STPK13; PLK1
Gene Aliases	PLK1
UniProt ID	P53350
Entrez Gene ID	5347

Product Description

PLK1 also known as PLK is a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. PLK1 plays a crucial role in cell cycle regulation, particularly during mitosis. PLK1 is predominantly located in the cytoplasm and accumulates during the S and G2 phases of the cell cycle, with levels peaking at the onset of mitosis before rapidly decreasing post-mitosis. PLK1 regulation is vital, as activity is closely linked to cell proliferation and the maintenance of genomic stability. Elevated expression of Plk has been observed in various tumors, suggesting potential as a biomarker for cancer progression and a target for therapeutic intervention.

Product Image Gallery
Western blot analysis of extracts on Hela, Jurkat cells, using PLK1 Rabbit Monoclonal Antibody (EAB21898) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol