Q86WV6

STING also known as TMEM173 is a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. STING protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. STING protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.