Polyclonal Antibodies - IRF-2 Rabbit Polyclonal Antibody

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IRF-2 Rabbit Polyclonal Antibody

Catalog #：EAB13115

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13115-30UL	In Stock	30ul	€115.70
EAB13115-100UL	In Stock	100ul	€258.70
EAB13115-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF=1:50-300
MW (kDa)	39
Conjugate	Unconjugate
Specificity	IRF-2 Rabbit Polyclonal Antibody detects endogenous levels of IRF-2 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Interferon regulatory factor 2; IRF-2; IRF2
Gene Aliases	IRF2
UniProt ID	P14316
Entrez Gene ID	3660

Product Description

IRF-2(Interferon regulatory factor 2) is a member of the interferon regulatory transcription factor (IRF) family. IRF-2 plays a crucial role in the regulation of immune responses by acting as a transcriptional repressor of interferon regulatory factor-1, thereby modulating the expression of type I interferons and interferon-inducible genes. This regulatory function is vital for maintaining the balance between immune activation and suppression, which is essential for preventing excessive inflammation and autoimmunity. IRF-2 is primarily located in the nucleus, where IRF-2 binds to specific DNA sequences in the promoters of target genes, influencing their transcriptional activity. Understanding the cellular localization of IRF-2 highlights IRF-2′s role in gene regulation and potential impact on cellular responses to viral infections and other immune challenges.

Product Image Gallery

Western blot analysis of extracts on COLO205, Jurkat cells, using IRF-2 Rabbit Polyclonal Antibody (EAB13115) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Predicted band size: 39 kDa; Observed band size: 47 kDa

Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma tissue, using IRF-2 Rabbit Polyclonal Antibody (EAB13115) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol