SKU-Pack Size | Availability | Size | Price | |
EAB13177-30UL | In Stock | 30ul | ¥1090.00 | |
EAB13177-100UL | In Stock | 100ul | ¥2290.00 | |
EAB13177-200UL | In Stock | 200ul | ¥3690.00 |
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北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IHC-P, IF, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
MW (kDa) | 14 |
Conjugate | Unconjugate |
Specificity | Phospho-α-Synuclein (Tyr125) Rabbit Polyclonal Antibody detects endogenous levels of α-Synuclein protein only when phosphorylated at Tyr125. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | alphaSYN; NACP; PARK1; PARK4; PD1; SNCA; Syn; Alpha-synuclein; α-Synuclein |
Gene Aliases | SNCA |
UniProt ID | |
Entrez Gene ID |
Product Description | |
α-synuclein is a pivotal protein primarily expressed in neuronal cell bodies and synapses, where α-synuclein plays a crucial role in synaptic regulation and neuronal plasticity, essential for maintaining proper brain function and facilitating communication between neurons. α-synuclein is deeply involved in synaptic vesicle trafficking and neurotransmitter release, processes vital for efficient neuronal signaling. α-synuclein is implicated in the pathogenesis of several neurodegenerative diseases, including Parkinson′s disease and Alzheimer′s disease, where abnormal aggregation is a hallmark of disease progression. Additionally, α-synuclein expression is modulated during hematopoietic cell differentiation, indicating broader significance in cellular processes beyond the nervous system. |
Product Image Gallery | |
![]() Western blot analysis of extracts on SH-SY5Y, 293 cells, using Phospho-α-Synuclein (Tyr125) Rabbit Polyclonal Antibody (EAB13177) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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Specific Protocols | |