Polyclonal Antibodies - Phospho-Rad18 (Ser403) Rabbit Polyclonal Antibody

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Phospho-Rad18 (Ser403) Rabbit Polyclonal Antibody

Catalog #：EAB13373

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13373-30UL	In Stock	30ul	￡119.90
EAB13373-100UL	In Stock	100ul	￡251.90
EAB13373-200UL	In Stock	200ul	￡405.90

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300
MW (kDa)	56
Conjugate	Unconjugate
Specificity	Phospho-Rad18 (Ser403) Rabbit Polyclonal Antibody detects endogenous levels of Rad18 protein only when phosphorylated at Ser403.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	RAD18 E3 ubiquitin protein ligase; RNF73; RAD18
Gene Aliases	RAD18
UniProt ID	Q9NS91
Entrez Gene ID	56852

Product Description

Rad18 plays a crucial role in post-replication repair of damaged DNA, which is vital for maintaining genomic stability and preventing mutations that could lead to cancer. Specifically, Rad18 is involved in recruiting ubiquitin-conjugating enzymes within the Rad6 pathway, facilitating modification of proteins essential for DNA repair processes. Rad18 interacts with other key proteins, such as Rad54, to ensure effective repair of chromosomal DNA. This interaction helps fill gaps in daughter strands during replication of damaged DNA, thereby preserving genetic material integrity. Rad18 is predominantly localized in the nucleus, where DNA damage response functions occur.

Product Image Gallery
Western blot analysis of extracts on Raji cells treated with UV, using Phospho-Rad18 (Ser403) Rabbit Polyclonal Antibody (EAB13373) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol