Polyclonal Antibodies - Amphiregulin/AREG Rabbit Polyclonal Antibody

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Amphiregulin/AREG Rabbit Polyclonal Antibody

Catalog #：EAB13658

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13658-30UL	In Stock	30ul	€115.70
EAB13658-100UL	In Stock	100ul	€258.70
EAB13658-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	28
Conjugate	Unconjugate
Specificity	Amphiregulin/AREG Rabbit Polyclonal Antibody detects endogenous levels of Amphiregulin/AREG protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Amphiregulin; AR; SDGF; AREGB; CRDGF; AREG
Gene Aliases	AREG
UniProt ID	P15514
Entrez Gene ID	374

Product Description

Amphiregulin also known as SDGF, AREG, CRDGF is a member of the epidermal growth factor family. Amphiregulin plays a crucial role in cellular signaling and is primarily produced by keratinocytes, where Amphiregulin functions as an autocrine growth factor. Amphiregulin is vital for normal human keratinocyte proliferation and binds to the ErbB-1 receptor, which is essential for the development of epithelial tissues in the skin, lungs, and gastrointestinal tract. Research has shown that withdrawal of Amphiregulin leads to downregulation of telomerase activity in human keratinocytes, indicating Amphiregulin′s role in regulating cellular aging processes.

Product Image Gallery
Western blot analysis of extracts on HBE cells, using Amphiregulin/AREG Rabbit Polyclonal Antibody (EAB13658) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol