Polyclonal Antibodies - BMPR1B Rabbit Polyclonal Antibody

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BMPR1B Rabbit Polyclonal Antibody

Catalog #：EAB13704

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB13704-100UL	In Stock	100ul	€258.70

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email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	56
Conjugate	Unconjugate
Specificity	BMPR1B Rabbit Polyclonal Antibody detects endogenous levels of BMPR1B protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Bone morphogenetic protein receptor type 1B; ALK6; AMD3; AMDD; BDA2; ALK-6; BDA1D; CDw293; BMPR1B
Gene Aliases	BMPR1B
UniProt ID	O00238
Entrez Gene ID	658

Product Description

BMPR1B also known as BMPR-IB, ALK6 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. BMPR1B plays a crucial role in the bone morphogenetic protein (BMP) signaling pathway, which regulates various biological processes, including cell differentiation, proliferation, and apoptosis. BMPR1B is primarily located on the cell membrane, where BMPR1B interacts with BMPs to form a signaling complex that activates downstream serine/threonine kinases. Proper functioning of BMPR1B is vital for maintaining normal bone development and homeostasis, as dysregulation of this pathway can lead to various pathologies, including cancer and bone disorders. BMPR1B is expressed in several tissues, including the brain and human glioma cell lines, highlighting BMPR1B′s importance in both normal physiology and disease states.

Product Image Gallery
Western blot analysis of extracts on U251MG, Mouse kidney cells, using BMPR1B Rabbit Polyclonal Antibody (EAB13704) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Immunohistochemistry of paraffin-embedded Human placenta tissue, using BMPR1B Rabbit Polyclonal Antibody (EAB13704) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol