CD79B also known as B29, Igbeta is a critical component of the B cell antigen receptor complex, functioning alongside CD79A to facilitate the signaling necessary for B cell activation and development. CD79B contains a cytoplasmic tail with an immuno-receptor tyrosine-based activation motif (ITAM) that is essential for initiating downstream signaling cascades upon antigen binding. This activation is crucial for B cell proliferation, differentiation, and the production of antibodies, making CD79B a vital player in adaptive immunity. The interaction of CD79B with membrane immunoglobulins, such as IgM and IgD, not only aids in their surface expression but also enhances their ability to present antigens effectively, thereby ensuring a robust immune response.