Polyclonal Antibodies - Acetyl-HNF4-α/γ (Lys127/79) Rabbit Polyclonal Antibody

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Acetyl-HNF4-α/γ (Lys127/79) Rabbit Polyclonal Antibody

Catalog #：EAB13905

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13905-30UL	In Stock	30ul	€141.70
EAB13905-100UL	In Stock	100ul	€297.70
EAB13905-200UL	In Stock	200ul	€479.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	52
Conjugate	Unconjugate
Specificity	Acetyl-HNF4-α/γ (Lys127/79) Rabbit Polyclonal Antibody detects endogenous levels of HNF4-α/γ protein HNF-4α/γ only when Acetyl occurs at Lys127(alpha)/79(gamma).
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Hepatocyte nuclear factor 4 alpha; Hepatocyte nuclear factor 4 gamma; TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; TCF-14; HNF4alpha; NR2A2; NR2A3; HNF4A; HNF4G
Gene Aliases	HNF4A/HNF4G
UniProt ID	P41235, Q14541
Entrez Gene ID	3172 , 3174

Product Description

HNF-4α/γ(Hepatocyte nuclear factor 4α/γ ) also known as HNF4A/HNF4G is a transcription factor that belongs to the orphan nuclear receptor superfamily. HNF-4α/γ plays an essential role in regulating genes involved in glucose and lipid metabolism, making it a key player in maintaining metabolic homeostasis. Dysfunction of HNF-4 α is associated with several metabolic disorders, including diabetes and obesity, highlighting its significance in both basic and clinical research. Understanding HNF-4 α function can provide insights into therapeutic targets for metabolic conditions. HNF4γ along with HNF1α regulates this transcriptome. HNF4γ generates and maintains enhancers at the gastrointestinal-lineage genes as a pioneer factor and mediates castration resistance.

Product Image Gallery
Western blot analysis of extracts on Mouse lung, Mouse kidney cells, using Acetyl-HNF4-α/γ (Lys127/79) Rabbit Polyclonal Antibody (EAB13905) at 1:500 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol