United Kingdom| SKU-Pack Size | Availability | Size | Price | |
| EAB14539-100UL | In Stock | 100ul | £251.90 | |
| EAB14539-200UL | In Stock | 200ul | £405.90 |
| Please select the country you are in to find your local distributor. |
| CUlabSciences | Phone:+44 (0) 1232 330008 | |
| Cambridge House St Thomas' Place Ely, | E-mail:sales@culabsciences.co.uk | |
| United Kingdom | Cambridge CB27 9RD UK | Web:www.culabsciences.co.uk |
| Product Information | |
| Applications | WB, IHC-P, IF, ELISA |
| Species Reactivity | Human, Mouse, Rat, Monkey |
| Host / Isotype | Rabbit IgG |
| Clonality | Polyclonal |
| Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| MW (kDa) | 81 |
| Conjugate | Unconjugate |
| Specificity | Phospho-Sp1 (Thr739) Rabbit Polyclonal Antibody detects endogenous levels of Sp1 protein only when phosphorylated at Thr739. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
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| Product Bioinformatics | |
| Synonym(s) | SP1; TSFP1; Transcription factor Sp1 |
| Gene Aliases | SP1 |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on COS7 cells treated with Serum, using Phospho-Sp1 (Thr739) Rabbit Polyclonal Antibody (EAB14539) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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| Specific Protocols | |