| SKU-Pack Size | Availability | Size | Price | |
| EAB14223-30UL | In Stock | 30ul | €115.70 | |
| EAB14223-100UL | In Stock | 100ul | €258.70 | |
| EAB14223-200UL | In Stock | 200ul | €440.70 |
| Please select the country you are in to find your local distributor. |
| Dianost | Phone£º+49 (0) 40 65472-053 | |
| Bullenkoppel 11£¬ 23896 Poggensee, | E-mail£ºola@olasciences.com | |
| Germany | Germany | Web£ºwww.olasciences.com |
| Product Information | |
| Applications | WB |
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit IgG |
| Clonality | Polyclonal |
| Applications Dilutions | WB=1:500-2000¡¡ ¡¡ |
| MW (kDa) | 177 |
| Conjugate | Unconjugate |
| Specificity | KDM6B/JMJD3 Rabbit Polyclonal Antibody detects endogenous levels of KDM6B/JMJD3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
|
| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
|
| Product Bioinformatics | |
| Synonym(s) | KDM6B; JMJD3; lysine demethylase 6B |
| Gene Aliases | KDM6B |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Enables beta-catenin binding activity; histone H3-tri/di-methyl-lysine-27 demethylase activity; and sequence-specific DNA binding activity. Involved in several processes, including histone H3-K27 demethylation; mesodermal cell differentiation; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cellular response to hydrogen peroxide; histone demethylation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including brain; gut; liver; metanephros; and olfactory epithelium. Orthologous to human KDM6B (lysine demethylase 6B). |
| Product Image Gallery | |
![]() Western blot analysis of extracts on different cells, using KDM6B/JMJD3 Rabbit Polyclonal Antibody (EAB14223) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: SH-SY5Y Lane2: K562 |
| Specific Protocols | |