Q13443

ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. ADAM9 plays a crucial role in various physiological processes, including cell adhesion and signaling. Notably, ADAM9 is involved in the modulation of Notch signaling pathways, which are essential for cell differentiation and development. ADAM9 structure includes a signal domain, pro domain, metalloprotease domain, disintegrin domain, cysteine-rich region, epidermal growth factor-like domain, transmembrane domain, and a cytoplasmic tail, all of which contribute to functional versatility. These domains allow ADAM9 to interact with specific proteins, facilitating processes such as fertilization and muscle fusion. Proper functioning of ADAM9 is vital for maintaining cellular communication and tissue homeostasis, making ADAM9 an important target for research in developmental biology and disease mechanisms.