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Phospho-PKC¦Ã (Thr514) Rabbit Monoclonal Antibody
Catalog #£ºEAB22085
  SKU-Pack Size Availability Size Price
EAB22085-100UL In Stock 100ul €336.70
If you want to get a larger packsize, Please contact your local distributor or
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SBT BioChem Srl Phone£º+39 05 7156 8147
Via Ponte di Bagnolo, 811 Bologna, E-mail£ºinfo@sbtbiochem.it
Italy Italy Web£ºwww.sbtbiochem.it
Product Information
Applications WB, IP, IHC-P
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Monoclonal
Applications Dilutions WB=1:500-2000¡¡
IP=1:10-100¡¡
IHC-P=1:50-200
MW (kDa) 78
Conjugate Unconjugate
Specificity Phospho-PKC¦Ã (Thr514) Rabbit Monoclonal Antibody detects endogenous levels of PKC¦Ã protein only when phosphorylated at Thr514
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) PRKCG; PKCG; Protein kinase C gamma type; PKC-gamma
Gene Aliases PRKCG
UniProt ID

P05129

Entrez Gene ID

5582

Product Description

PKCγ also known as PKCgamma, PRKCG is a member of the protein kinase C family. PKCγ plays a crucial role in regulating numerous cellular processes such as cell growth, differentiation, and apoptosis. A C1 domain that binds diacylglycerol and phorbol esters characterizes PKCγ structure, allowing activation in response to specific signaling molecules, making PKCγ essential for mediating cellular responses to growth factors and hormones. Distinct expression patterns of PKCγ across different tissues highlight PKCγ importance in tissue-specific signaling pathways, and PKCγ ability to interact with various proteins, including Ras and Rho GTPases, underscores PKCγ role in modulating cytoskeletal dynamics and cell motility. PKCγ versatility in cellular signaling makes PKCγ a significant target for research into cancer and other diseases, where PKCγ dysregulation can lead to altered cell behavior and contribute to tumorigenesis.

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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