P29317

EphA2 is a member of the Eph receptor family, which represents the largest group of receptor protein tyrosine kinases identified to date, playing a crucial role in various biological processes, including cell signaling, development, and the functioning of the central nervous system. EphA2 protein is primarily located on the cell surface, where EphA2 interacts with ephrin-A2 and ephrin-A4 ligands to mediate bidirectional signaling that influences cell adhesion, migration, and tissue organization. This spatial localization is vital as EphA2 participates in the regulation of cellular interactions and communication, which are essential for processes such as angiogenesis and neural development.