Polyclonal Antibodies - Acetyl-Src-3 (Lys616) Rabbit Polyclonal Antibody

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Acetyl-Src-3 (Lys616) Rabbit Polyclonal Antibody

Catalog #：EAB13317

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13317-30UL	In Stock	30ul	￡119.90
EAB13317-100UL	In Stock	100ul	￡251.90
EAB13317-200UL	In Stock	200ul	￡405.90

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	155
Conjugate	Unconjugate
Specificity	Acetyl-Src-3 (Lys616) Rabbit Polyclonal Antibody detects endogenous levels of Src-3 protein only when acetylated at Lys616.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Nuclear receptor coactivator 3; ACTR; AIB1; RAC3; SRC3; pCIP; AIB-1; CTG26; SRC-3; CAGH16; KAT13B; TNRC14; TNRC16; TRAM-1; bHLHe42; NCOA3
Gene Aliases	NCOA3
UniProt ID	Q9Y6Q9
Entrez Gene ID	8202

Product Description

Src-3 also known as RAC3, ACTR, AIB-1, p/CIP, NCoA-3, plays a crucial role as a transcriptional coactivator in the steroid receptor family, facilitating the transcriptional activation of hormone-responsive genes. NCoA-3 is particularly significant due to its involvement in the regulation of gene expression linked to various physiological processes, including cell growth and differentiation. Notably, NCoA-3 is often overexpressed in estrogen receptor-positive ovarian and breast cancers, highlighting its importance in cancer biology and potential as a therapeutic target. The interaction of NCoA-3 with other proteins, such as p300/CBP, underscores its role in enhancing transcriptional activity, making NCoA-3 a vital component in the signaling pathways that govern cellular responses to hormones.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol