P30304

CDC25A is a member of the CDC25 family of phosphatases. Cdc25A plays a crucial role in cell cycle regulation, particularly in the transition from G2 phase to mitosis, by acting as a phosphatase that dephosphorylates and activates the cyclin-dependent kinase Cdc2. This activation is essential for the proper progression of mitosis, as it allows the cell to enter the mitotic phase and ensures accurate chromosome segregation. Dysregulation of Cdc25A can lead to uncontrolled cell division and has been implicated in various cancers, making Cdc25A a significant target for therapeutic intervention. Cdc25A is primarily located in the nucleus, where Cdc25A interacts with other cell cycle regulators, and Cdc25A activity is tightly controlled by phosphorylation and dephosphorylation events.