Recombinant Antibodies - Atg14 Rabbit Monoclonal Antibody

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Atg14 Rabbit Monoclonal Antibody

Catalog #：EAB22634

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22634-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Cambiotech	Phone：+44 (0) 188 448801
	Lanwades Business Park,	E-mail：info@cambiotech.com
Ireland	Kobenhavn K, Ireland	Web：www.cambiotech.com

Product Information
Applications	WB, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　　 IF/ICC=1:100-500
MW (kDa)	55
Conjugate	Unconjugate
Specificity	Atg14 Rabbit Monoclonal Antibody detects endogenous levels of Atg14 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Autophagy related 14; ATG14L; BARKOR; KIAA0831; ATG14
Gene Aliases	ATG14
UniProt ID	Q6ZNE5
Entrez Gene ID	22863

Product Description

Atg14 also known as ATG14L is a core component of the class III phosphatidylinositol 3-kinase (PI3KC3) complex I that directs phosphatidylinositol 3-phosphate production at the endoplasmic reticulum to initiate autophagosome nucleation. By coupling Beclin 1–VPS34 signaling to early autophagy membrane dynamics, Atg14 supports autophagosome biogenesis, selective autophagy, and cellular adaptation to nutrient and proteotoxic stress. Disruption of ATG14-dependent autophagy has been linked to altered proteostasis, mitochondrial quality control, and inflammatory signaling, processes frequently studied in cancer biology, neurodegeneration, and metabolic stress models.

Product Image Gallery
Western blot analysis of extracts on Hela, NIH/3T3, HEK293 cells, using Atg14 Rabbit Monoclonal Antibody (EAB22634) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 55 kDa; Observed band size: 65 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol