Polyclonal Antibodies - Phospho-Rictor (Thr1135) Rabbit Polyclonal Antibody

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Phospho-Rictor (Thr1135) Rabbit Polyclonal Antibody

Catalog #：EAB11007

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11007-30UL	In Stock	30ul	$163.50
EAB11007-100UL	In Stock	100ul	$343.50
EAB11007-200UL	In Stock	200ul	$553.50

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300
MW (kDa)	192
Conjugate	Unconjugate
Specificity	Phospho-Rictor (Thr1135) Rabbit Polyclonal Antibody detects endogenous levels of Rictor only when phosphorylated at Thr1135.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	PIA; AVO3; hAVO3
Gene Aliases	RICTOR
UniProt ID	Q6R327
Entrez Gene ID	253260

Product Description

Rictor shares homology with pianissimo from D. discoidieum, STE20p from S. pombe, and AVO3p from S. cerevisiae. Rictor forms a complex with FRAP, which is important in cell growth regulation as it integrates growth factor and nutrient derived signals. The Rictor-FRAP complex plays a role in PKCα phosphorylation, directly phosphorylates Akt/PKB on Ser473 in vitro and facilitates Thr308 phosphorylation by PDK1. It also may function as a drug target in tumors that have lost expression of PTEN, a tumor suppressor that opposes activation of Akt/PKB.

Product Image Gallery
Western blot analysis of extracts on NIH/3T3 cells treated with Heat shock, using Phospho-Rictor (Thr1135) Rabbit Polyclonal Antibody (EAB11007) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol