Polyclonal Antibodies - Cytokeratin 18 Rabbit Polyclonal Antibody

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Cytokeratin 18 Rabbit Polyclonal Antibody

Catalog #：EAB11166

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11166-30UL	In Stock	30ul	￡97.90
EAB11166-100UL	In Stock	100ul	￡218.90
EAB11166-200UL	In Stock	200ul	￡372.90

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IP, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:1000-5000　 IP=1:20-200 IHC-P=1:100-500　 IF/ICC=1:100-500
MW (kDa)	47
Conjugate	Unconjugate
Specificity	Cytokeratin 18 Rabbit Polyclonal Antibody detects endogenous levels of Cytokeratin 18 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Cytokeratin-18; keratin 18; K18; CK-18; CYK18; KRT18
Gene Aliases	KRT18
UniProt ID	P05783
Entrez Gene ID	3875

Product Description

Cytokeratin 18 also known as CK-18, Keratin 18, KRT18 is a vital component of the cytoskeleton in epithelial cells, Cytokeratin 18 playing a crucial role in maintaining cell integrity and providing mechanical support. Cytokeratin 18 is primarily located in the cytoplasm of epithelial cells, where proper localization is essential for cellular architecture and function. Disruption of Cytokeratin 18 localization can lead to compromised cell stability and has been implicated in various pathological conditions, including cancer. Cytokeratin 18 serves as a significant marker for adenocarcinomas and basal cell carcinomas, making Cytokeratin 18 an important target for cancer diagnostics and research.

Product Image Gallery

Western blot analysis of extracts on Hela, 293T, L929, COLO205, Mouse brain cells, using Cytokeratin 18 Rabbit Polyclonal Antibody (EAB11166) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Immunohistochemical analysis of paraffin-embedded Mouse kidney tissue, using Cytokeratin 18 Rabbit Polyclonal Antibody (EAB11166) at 1:200 dilution.

Immunofluorescence analysis of Mouse kidney tissue, using Cytokeratin 18 Rabbit Polyclonal Antibody (EAB11166)(red) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol