Polyclonal Antibodies - MAGE-C2 Rabbit Polyclonal Antibody

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MAGE-C2 Rabbit Polyclonal Antibody

Catalog #：EAB11210

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11210-30UL	In Stock	30ul	€115.70
EAB11210-100UL	In Stock	100ul	€258.70
EAB11210-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	41
Conjugate	Unconjugate
Specificity	MAGE-C2 Rabbit Polyclonal Antibody detects endogenous levels of MAGE-C2 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	MAGE family member C2; CT10; HCA587; MAGEE1; MAGEC2
Gene Aliases	MAGEC2
UniProt ID	Q9UBF1
Entrez Gene ID	51438

Product Description

MAGE-C2 also known as CT10 is related to members of the MAGEC gene family. It is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. MAGE-C2 a cancer-testis antigen with restricted expression in normal germline tissues and frequent re-expression in diverse tumors. MAGE-C2 participates in protein homeostasis by engaging ubiquitin-dependent processes, including modulation of E3 ligase activity through interactions with RING-domain partners, thereby influencing stability of signaling and cell-cycle regulators. Dysregulated MAGE-C2 expression has been linked to altered proliferation, stress responses, and transcriptional programs associated with malignant progression and immune recognition.

Product Image Gallery
Western blot analysis of extracts on Hela, SH-SY5Y, 293T, Mouse brain cells, using MAGE-C2 Rabbit Polyclonal Antibody (EAB11210) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol