Polyclonal Antibodies - PHLDA2 Rabbit Polyclonal Antibody

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PHLDA2 Rabbit Polyclonal Antibody

Catalog #：EAB22694

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22694-100UL	In Stock	100ul	￡218.90

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, ELISA
Species Reactivity	Human
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　　 IHC-P=1:50-300
MW (kDa)	17
Conjugate	Unconjugate
Specificity	TSSC3 Rabbit Polyclonal Antibody detects endogenous levels of TSSC3 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Pleckstrin homology like domain family A member 2; IPL; BRW1C; BWR1C; HLDA2; TSSC3; PHLDA2
Gene Aliases	PHLDA2
UniProt ID	Q53GA4
Entrez Gene ID	7262

Product Description

PHLDA2 also known as TSSC3 is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. PHLDA2 plays a crucial role in regulating fetal and placental growth, making PHLDA2 essential for normal human development. This cytoplasmic protein is predominantly expressed in the placenta and adult prostate, with lower levels found in the liver, lung, and brain. PHLDA2 functions as an apoptosis-related protein and acts as a negative growth regulator, which is vital for maintaining cellular homeostasis during development. Notably, PHLDA2 is imprinted on the placenta, liver, and fetal tissues during embryogenesis, and PHLDA2 expression is tightly regulated, being removed once development is complete.

Product Image Gallery
Western blot analysis of extracts on 293T, HepG2 cells, using PHLDA2 Rabbit Polyclonal Antibody (EAB22694) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue, using PHLDA2 Rabbit Polyclonal Antibody (EAB22694) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol