Polyclonal Antibodies - Erk2 Rabbit Polyclonal Antibody

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Erk2 Rabbit Polyclonal Antibody

Catalog #：EAB11262

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11262-30UL	In Stock	30ul	€115.70
EAB11262-100UL	In Stock	100ul	€258.70
EAB11262-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	42
Conjugate	Unconjugate
Specificity	Erk2 Rabbit Polyclonal Antibody detects endogenous levels of Erk2 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Mitogen-activated protein kinase 1; ERK; p38; p40; p41; ERK2; ERT1; NS13; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK; MAPK1
Gene Aliases	MAPK1
UniProt ID	P28482
Entrez Gene ID	5594

Product Description

ERK2 also known as P42, MAPK1 is a member of the MAP kinase family. ERK2 is a pivotal component of the MAPK/ERK signaling pathway, which transmits extracellular signals from growth factors, hormones, and neurotransmitters to elicit cellular responses. Activation of ERK2 occurs via phosphorylation by upstream kinases like MEK1/2, leading to dimerization and translocation into the nucleus. Once in the nucleus, ERK2 phosphorylates various transcription factors and regulatory proteins, influencing gene expression related to cell proliferation, differentiation, survival, and development. Dysregulation of ERK2 activity has been implicated in numerous pathological conditions, including cancer and neurodegenerative diseases, making ERK2 a significant focus in biomedical research.

Product Image Gallery

Western blot analysis of extracts on HuvEc, HEK293, NIH/3T3 cells, using Erk2 Rabbit Polyclonal Antibody (EAB11262) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue, using Erk2 Rabbit Polyclonal Antibody (EAB11262) at 1:200 dilution.

Immunofluorescence analysis of MCF7 cell, using Erk2 Rabbit Polyclonal Antibody (EAB11262) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol