DVL3(Dishevelled 3) is a member of the dishevelled protein family. DVL3 plays a crucial role in the Wnt signaling pathway, which regulates cell proliferation, differentiation, and embryonic development. Disruption of DVL3 function has been implicated in various developmental disorders and cancers, making DVL3 a significant target for research in understanding these diseases. DVL3 interacts with several key proteins, including frizzled receptors and axin, which are vital for proper functioning of the Wnt pathway. These interactions underscore DVL3′s importance in maintaining cellular homeostasis and potential as a therapeutic target in Wnt-related pathologies.