Monoclonal Antibodies - MST2 Mouse Monoclonal antibody

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MST2 Mouse Monoclonal antibody

Catalog #：EAB22512

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22512-100UL	In Stock	100ul	￡284.90

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email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Mouse IgG2a
Clonality	Monoclonal
Applications Dilutions	WB=1:5000-20000 IHC-P=1:100-500 IF/ICC=1:200-1000
MW (kDa)	56
Conjugate	Unconjugate
Specificity	MST2 Mouse Monoclonal Antibody detects endogenous levels of MST2 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Serine/threonine kinase 3; KRS1; MST2; STK3
Gene Aliases	STK3
UniProt ID	Q13188
Entrez Gene ID	6788

Product Description

MST2 also known as KRS1, STK3 is Krs-1 is a member of the mammalian Ste20-like kinases, which are part of the GCK subfamily of serine/threonine kinases. MST2 plays a crucial role in cellular signaling pathways, particularly in the regulation of apoptosis and cell proliferation. MST2 is primarily located in the cytoplasm and can translocate to the nucleus under certain conditions, which is significant for modulating various signaling cascades, including those activated by G protein-coupled receptors. MST2 phosphorylates specific substrates, including itself, allowing participation in the activation of downstream effectors such as ERK and JNK, which are vital for cellular responses to stress and growth signals.

Product Image Gallery
Western blot analysis of extracts on Hela, Jurkat, HEK293, NIH/3T3 cells, using MST2 Mouse Monoclonal Antibody (EAB22512) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol