| SKU-Pack Size | Availability | Size | Price | |
| EAB22444-100UL | In Stock | 100ul | ¥2290.00 |
| Please select the country you are in to find your local distributor. |
| 北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
| 2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
| China | Beijing China | Website: www.mrkbio.com |
| Product Information | |
| Applications | WB, IHC-P, IF/ICC |
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse IgG1 |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| MW (kDa) | 62 |
| Conjugate | Unconjugate |
| Specificity | Neurofilament-L Mouse Monoclonal Antibody detects endogenous levels of Neurofilament-L protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
|
| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
|
| Product Bioinformatics | |
| Synonym(s) | Neurofilament light chain; NFL; NF-L; NF68; CMT1F; CMT2E; CMTDIG; PPP1R110; NEFL |
| Gene Aliases | NEFL |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on different cells, using Neurofilament-L Mouse Monoclonal Antibody (EAB22444) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: Hela Lane2: Mouse brain ![]() Immunohistochemical analysis of paraffin-embedded Human hippocampus tissue, using Neurofilament-L Mouse Monoclonal Antibody (EAB22444) at 1:200 dilution.
|
| Specific Protocols | |