Polyclonal Antibodies - Phospho-Caldesmon (Ser789) Rabbit Polyclonal Antibody

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Phospho-Caldesmon (Ser789) Rabbit Polyclonal Antibody

Catalog #：EAB11515

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11515-30UL	In Stock	30ul	￡119.90
EAB11515-100UL	In Stock	100ul	￡251.90
EAB11515-200UL	In Stock	200ul	￡405.90

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email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	93
Conjugate	Unconjugate
Specificity	Phospho-Caldesmon (Ser789) Rabbit Polyclonal Antibody detects endogenous levels of Caldesmon protein only when phosphorylated at Ser789.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Caldesmon 1; CDM; HCAD; LCAD; h-CD; H-CAD; L-CAD; NAG22; CALD1
Gene Aliases	CALD1
UniProt ID	Q05682
Entrez Gene ID	800

Product Description

Caldesmon also designated CALD1, CDM is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Product Image Gallery

Western blot analysis of extracts on Hela cells treated with EGF, using Phospho-Caldesmon (Ser789) (EAB11515) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.

Predicted band size: 93 kDa; Observed band size: 80 kDa

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using Phospho-Caldesmon (Ser789) (EAB11515) at 1:100 dilution.

Immunofluorescence analysis of Hela cell, using Phospho-Caldesmon (Ser789) (EAB11515) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol