SKU-Pack Size | Availability | Size | Price | |
EAB22378-100UL | In Stock | 100ul | £251.90 |
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CUlabSciences | Phone:+44 (0) 1232 330008 |
Cambridge House St Thomas' Place Ely, | E-mail:sales@culabsciences.co.uk | |
United Kingdom | Cambridge CB27 9RD UK | Web:www.culabsciences.co.uk |
Product Information | |
Applications | WB, IHC-P, IF/ICC, FC |
Species Reactivity | Human, Mouse |
Host / Isotype | Rabbit IgG |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:50-200 FC=1:10-100 |
MW (kDa) | 86 |
Conjugate | Unconjugate |
Specificity | Gelsolin Rabbit Monoclonal Antibody detects endogenous levels of Gelsolin protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Gelsolin; ADF; AGEL; AMYLD4; GSN |
Gene Aliases | GSN |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Gelsolin plays a crucial role in regulating actin filament dynamics, which is essential for various cellular processes, including motility, shape maintenance, and intracellular transport. By severing actin filaments in the presence of calcium, Gelsolin facilitates cytoskeleton remodeling, allowing cells to respond effectively to environmental cues. This dynamic regulation is particularly important in leukocytes and platelets, where actin rearrangement is vital for immune responses and clot formation. Gelsolin′s ability to exist in both secreted and intracellular forms highlights its versatility and importance in maintaining cellular homeostasis. |
Product Image Gallery | |
![]() Western blot analysis of extracts on HepG2, Mouse liver, Mouse lung cells, using Gelsolin Rabbit Monoclonal Antibody (EAB22378) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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Specific Protocols | |